Ana has many years of experience in clinical research and health advising. It has been studied for its effects on everything from mental function to treating high blood pressure. Pycnogenol treatment led to significantly better improvement in the lung function and asthma symptoms. The researchers concluded that pine bark extract may increase production of hyaluronic acid and collagen, which are both found in many popular antiaging products. Today, I want to share with you my secrets to reduce sugar Top 7 Benefits of Green Tea: The No. Align your health hacks with your genes for optimal health & cognitive function. Moreover, Pycnogenol group either reduced or discontinued the use of asthma drugs. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. Traditionally, people might drink a brew made from pine bark -- rich in pycnogenol -- as a treatment. $31.99. Chemistry. In one human study, some of the reported side effects of chanca piedra supplementation included: abdominal pain. Start with a low dose so you can be sure it doesnt cause any side effects. Most anal fissures heal with home treatment after a few days or weeks. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. Low-dose Pycnogenol (30 mg/day) may reduce pain in pregnant women, particularly hip, joint, lower back, groin, and calf cramps in the third trimester [71]. Its best to check with your doctor about the dosage, based on the symptoms you have and other possible conditions, prior to taking either pine bark extract or Pycnogenol. A trial of 84 people found that both Pycnogenol oral supplements and creams (0.5%) may prevent hemorrhoids from bleeding during acute attacks after 7 days. But what are its health benefits? If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. Moreover, Pycnogenol treatment reduced the use of painkillers. (8). High levels of both of these are considered risk factors for heart disease. are clickable links to these studies. 11 Skin elasticity increased, and skin fatigue decreased significantly in this study as well, further lowering the wrinkling risk. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. The study showed that many people who participated had a drop in their systolic blood pressure after taking Pycnogenol. They also had normalized fasting glucose levels and blood pressure, which can also reduce a persons risk of heart problems. COPD. Erectile dysfunction has increased over the past decade or two, creating a pathway for various medications to land on the shelves of numerous medicine cabinets. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Grape seed extract may have heart-health benefits. In a good-quality study, 77 patients with osteoarthritis were treated with 100 mg of Pycnogenol daily and 79 patients were treated with placebo for three months. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation. DOI: Dvorkov M, et al. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. Pycnogenol has been shown to help relieve the pain associated with osteoarthritis by keeping blood chemicals from attacking the cartilage. 4. What Are These Tiny Red Spots on My Skin (Petechiae)? Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. It also may enhance swimming, biking, and running scores in professional athletes preparing for a triathlon (at 150 mg/day). 2005 - 2023 WebMD LLC. In a good-quality study, 24 adults aged 24 to 53 years old with attention deficit hyperactivity disorder (ADHD) were given Pycnogenol, placebo, or the standard drug for three weeks. painful urination. Are there any risks to taking it? 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. Pycnogenol (150 mg/day) reduced LDL and increased HDL cholesterol in a trial of 25 healthy people after 6 weeks [55]. . Here are the many health benefits believed to be possible with Pycnogenol: Now lets dive into the first condition it could help treat. (adsbygoogle = window.adsbygoogle || []).push({}); Heart Palpitations at Night: Common Causes and How to Treat, Essential Oils for Cough, Cold and Congestion, Sudden High Blood Pressure: Causes, Symptoms and Prevention Tips, Sore Throat on One Side: 7 Causes and Treatments, Natural Remedies for the Burning Sensation in Your Stomach After Eating, Hibiscus Tea: Health Benefits, Nutrition, Side Effects, and Recipes, Vegetable Oil Substitutes: 5 Healthy Alternatives for Baking, Frying, and More, How to Treat Nausea After Eating Eggs or Chicken, Diarrhea after Eating: Causes and Natural Treatments, Top 11 Homeopathic Remedies for High Blood Pressure, Heavy Breathing: Common Causes and Treatments, Pineapple Juice for Cough: Effective Homemade Cough Remedies, Pain in the Left Temple of the Head: 10 Causes and Treatments. In addition to general healthy eating, some specific vitamins and minerals may help improve ADHD. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. A clinically studied blend of Pycnogenol and a special bilberry extract (called Mirtogenol ) has been shown to provide benefits for vision and eye health. Studies have also safely used Pycnogenol in children and during pregnancy. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Pycnogenol may stimulate the immune system. Sign Up for the Latest Health News and Tips, Home Food and Nutrition Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies. Researchers suggest this benefit may be due to an increase in glutathione and SOD, two antioxidants that may reduce inflammation and oxidative stress in Crohns [76]. However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. (7). Rating: 100%. Not bad. These benefits appeared to persist for some time even after stopping supplementation [72]. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. 1. from the bark of the French maritime pine tree. Pycnogenol-treated patients reported significant improvement with knee pain, as compared to the placebo group. ( 1) 2. Typical doses range from 50 milligrams to 450 milligrams per day. Researchers suggest this effect may be due to reduced dopamine and adrenaline levels and increased glutathione levels. However, it is also important to see beyond the pyncogenol marketing campaign and understand the possible dangers associated with this natural supplement. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. Risks. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. This supplement may also increase muscle endurance and performance after a single pre-exercise dose according to a study of 9 cyclists [12, 13]. Its used as a natural supplement for several conditions, including dry skin and ADHD. Pine bark extract comes from the inner bark of the Pinus pinaster tree, most commonly found in Europe. If you knew you could resolve your erectile dysfunction and, therefore, naturally remedy impotence issues, wouldnt you? If youre native to Oregon, you likely know all about marionberries. Millions are hospitalized each year for . Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. We believe that the most accurate information is found directly in the scientific source. It may cause side effects such as: Dizziness. Seems like it must be pretty amazing, but lets look closer. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [58, 59]. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? Pycnogenol acts as a sustained-release formulation. For asthma in children: 1 milligram per pound of body weight given in two divided doses. It also provides powerful antioxidant protection and helps inhibit inflammatory factors to support. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. DOI: Gulati OP. It comes from the bark of a European pine tree. There are several causes for erectile dysfunction, such as neurological and psychological issues. More specifically, because it strengthens the capillaries in the retina, Mirtogenol can help prevent retinopathy. A good-quality study was conducted in 77 diabetic patients who received their standard antidiabetic treatment along with 100 mg Pycnogenol a day or placebo for 12 weeks. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. Inhibits platelet aggregation like low-dose aspirin. The results of a 2013 animal study suggest that pine bark extract may help to reduce damage to nerve cells following a traumatic brain injury. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. Pycnogenol (125 mg/day) had the same effects in another study of 48 people with diabetes and high blood pressure. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . This nerve affects our balance and hearing by sending signals to the brain. One way to add some extra flavor and nutrients to your day is by adding prune juice to your diet. Prunes and prune juice have many health benefits. The combination of Panax ginseng and vitamin E also appears to have an effect. For diseases of the retina, including those related to diabetes: 50 milligrams three times daily. Joe Cohen flipped the script on conventional and alternative medicine and it worked. Arginine is a non-essential amino acid because most humans can make it in their bodies. A clinical trial of 60 health professionals found that Pycnogenol (150 mg/day) may improve cognitive function, attention, mental performance and specific professional skills after 12 weeks. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. In another study, 61 children with ADHD were given one mg per kg/day of Pycnogenol or placebo over four weeks. In a study of 72 children undergoing cancer chemotherapy, Pycnogenol reduced painful mouth ulcers, both alone and in combination with vitamin E [79]. A small 2012 study on postmenopausal women found that pine bark extract improved hydration and elasticity of skin. (2004). We don't yet know what the best dose to use is, but studies have used two 50 mg Pycnogenol capsules per day. Forty-seven Japanese men with mild erectile dysfunction were given supplementation L-arginine and French maritime pine bark extract over a period of time. Thirty patients with diabetic ulcers were treated with 150 mg Pycnogenol daily for four weeks and another group of 30 comparable patients received no treatment. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". Your email address will not be published. If you are thinking of taking Pycnogenol for a serious health condition like asthma or high blood pressure, check with your doctor., People who have autoimmune conditions like multiple sclerosis or lupus should talk to their doctor before trying Pycnogenol. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10. This includes supporting healthy blood circulation, acting as a natural anti-inflammatory, helping to generate collagen and hyaluronic acid for improved skin health and aiding in the production of endothelial nitric oxide which helps to dilate blood . Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. We all know the power of antioxidants to improve health and thehigh-antioxidant foodswe should eat regularly. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. Here are 12 benefits of ginkgo biloba. $109.99. 2. Side Effects of Pycnogenol. In this study, 155 peri-menopausal women were enrolled in a double-blind, placebo-controlled study. Pycnogenol is the US trademarked name for an antioxidant made from Mediterranean tree bark. (2012). Pine bark extract has been studied regarding its relationship to exercise performance, oxidative stress and inflammation to body that has been imposed by exercise. Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. A randomized placebo-controlled trial of 60 children with mild-to-moderate asthma found that those who took Pycnogenol may be able to reduce or discontinue their use of rescue inhalers more often than the placebo group [15]. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). Pycnogenol significantly reduced the swelling as well as the feeling of heaviness. In contrast, almost 20% of the participants on inhalers alone had to increase their dosage. Regardless of what youre using it for, its best to start with the lowest possible dose. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. Jonathan Ritter, PharmD, PhD (Pharmacology), Small molecule antioxidants (phenolic acids, catechin, and taxifolin) are quickly absorbed and begin to act in the body within 30 min, The remaining more complex antioxidants (long chains of procyanidins) reach the gut, where your, The microbiome-produced active compounds appear in blood 6 h later and remain for at least 14 h, Pycnogenol is standardized to contain 70 5% procyanidins, which should be on the label, Pycnogenol standardization doesnt determine other major active compounds, which can vary. We do not aim to diagnose, treat, cure or prevent any illness or disease.