Some rare cases can take up to three months. J Eur Acad Dermatol Venereol. COVID-19; HHV, human herpes virus; Moderna; PR; PR, pityriasis rosea; PR-LE; PR-LE, pityriasis rosea-like eruption; Pfizer; coronavirus; dermatology; mRNA vaccine; mRNA, messenger RNA; pityriasis rosea; pityriasis rosealike eruption; vaccine. J Med Virol 2021; 93: 1850-1851. -, Mahajan K, Relhan V, Relhan AK, et al. This site needs JavaScript to work properly. eCollection 2022. (b) Patient 1: Closeup of a plaque. About one to two weeks later, discolored circular or oval-shaped patches appear in groups near the herald patch. For instance, the rash sometimes appears only under the arms or on the flanks. PMC 2021;85(1):4655. N Engl J Med 2020; 383: 26032615. The https:// ensures that you are connecting to the Some patients may have a cold before the rash. This site needs JavaScript to work properly. Pityriasis rosea: Signs and symptoms - American Academy of Dermatology According to King, an in-person skin exam is usually enough to make an accurate diagnosis, though a biopsy or blood work may be necessary for some. Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review. Numerous scattered erythematous, Pityriasis rosea. Your California Privacy Rights. We do not endorse non-Cleveland Clinic products or services. sharing sensitive information, make sure youre on a federal Authors Lina Abdullah 1 "However, it's possible to develop the rash more than once," she says. Refined carbohydrates, such as sugar, pastries and white bread. Khalili M, Abtahi-Naeini B, Rastegarnasab F, Afshar K. Clin Case Rep. 2022 Jul 19;10(7):e6096. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature. The papulovesicular and pityriasis rosea . COVID-19: Cutaneous manifestations and issues related to - UpToDate Histopathological findings of pityriasis rosealike eruption in patient 1. Drago F, Ciccarese G, Rebora A, Parodi A. Epub 2022 Jun 21. The herald patch is the telltale sign that your rash could be PR, but there are other common (though not universal) symptoms as well. It is likely that a new viral trigger of pityriasis rosea is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). doi: 10.1111/dth.15040, 3. Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Int J Dermatol. JAAD Case Rep. (2018) 4:8001. Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. Pityriasis rosea often occurs this way, but not always. Physicians should be aware that pityriasis rosea is a rare side-effect of COVID-19 vaccination.Pityriasis rosea is self-limiting and no medical treatment is usually required. Human herpesvirus6, 7, and EpsteinBarr virus reactivation in pityriasis rosea during COVID19. The .gov means its official. Epub 2022 Feb 9. Authors Jordan E Buckley 1 , Laura N Landis 2 , Ronald P Rapini 1 Affiliations Disclaimer. J Investig Dermatol 2005;124:123440. Use of this site constitutes acceptance of our The appearance of pityriasis rosea following the first injection of the AstraZeneca vector vaccine suggests a causal connection. You also wont have permanent scarring or other damage to your skin. -, Busto-Leis J.M., Servera-Negre G., Mayor-Ibarguren A., et al. Pityriasis rosea after Moderna mRNA-1273 vaccine: A case series While my particular flare-up itched a lot, that's not always the case. The most commonly reported features . 2021 Jul;85(1):46-55. doi: 10.1016/j.jaad.2021.03.092. J Med Virol. Please enable it to take advantage of the complete set of features! If you develop symptoms of pityriasis rosea while pregnant, contact your healthcare provider right away. The site is secure. Pityriasis rosea doesnt usually affect people over the age of 60. government site. A 3-cm oval plaque with peripheral scale, larger than the other lesions, was present on the inferior portion of the right breast. HHS Vulnerability Disclosure, Help See this image and copyright information in PMC. Coronavirus: Five skin conditions linked to COVID-19 after - 9News Ciccarese G, Parodi A, Drago F. SARS-CoV-2 as possible inducer of viral reactivations. headache.2 Several cutaneous adverse events after anti-COVID-19 vaccination are described in the literature, such as delayed large local reaction, urticaria, morbilliform eruptions, herpes zoster, "COVID arm," pityriasis rosea.3,4,5 Here, we report a case of a patient who presented with herpes zoster ophthalmicus (HZO) after the third dose doi: 10.1111/bjd.20143. doi: 10.1002/ccr3.6096. eCollection 2022. When to test for COVID-19 using real-time reverse transcriptase polymerase chain reaction: a systematic review. J Eur Acad Dermatol Venereol. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Blumenthal KG, Fox LP, Freeman EE. doi: 10.1111/jdv.17316, PubMed Abstract | CrossRef Full Text | Google Scholar, 2. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. 2021;184(6):11941195. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. PMC I video-chatted with my dermatologist who asked a few questions: Did I have body aches or flu-like symptoms? 2021 Nov 2;17(11):4097-4098. doi: 10.1080/21645515.2021.1963173. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. You cant spread pityriasis rosea to another person through unprotected sex or skin-to-skin contact. J Am Acad Dermatol. 8:752443. doi: 10.3389/fmed.2021.752443. Accessibility 2021 Sep 7;8:752443. doi: 10.3389/fmed.2021.752443. 2023 Cond Nast. See your skin clear. Human herpesvirus-6, -7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. Dos Santos PG, Vieira HCVS, Wietholter V, Gallina JP, Andrade TR, Marinowic DR, Zanirati GG, da Costa JC. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry-based study of 414 cases. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. User Agreement and Privacy Policy and Cookie Statement and Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. -, Carballido Vzquez A.M., Morgado B. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Disclaimer. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Common causes of drug-induced PR-like eruptions include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, and gold. The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s. 2022 Oct;49(10):948-956. doi: 10.1111/1346-8138.16482. National Library of Medicine doi: 10.1111/j.0022-202X.2005.23719.x. Would you like email updates of new search results? PR also tends to occur in patients between the ages of 10 to 35 that are usually otherwise healthy, Lam says. Br J Dermatol. Copyright 2021 the Author(s). Epub 2022 Oct 17. Epub 2020 Jun 5. doi: 10.1111/dth.13650, 7. Histopathologic examination revealed epidermal focal spongiosis, interface dermatitis with necrotic keratinocytes, perivascular lymphocytic infiltration, and few eosinophilic infiltrations in the superficial dermis (Figures 3B,C). Fortunately, PR-like eruption is responsive to topical corticosteroids without any systemic adverse effects. The site is secure. -. Now watch a pro surfer's entire daily routine: Follow Allure onInstagram andTwitter, orsubscribe to our newsletter to stay up to date on all things beauty. Before Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Pityriasis Rosea Following Pfizer-BioNTech Vaccination in an Adolescent Girl. Physical examination revealed that lesions were distributed along cleavage lines, similar to PR, without herald patch or prominent scales (Figure 1C). Dermatol Online J. Epub 2022 Feb 9. New York City-based dermatologist Macrene Alexiades. Epub 2021 Aug 7. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. This site needs JavaScript to work properly. ", The 29 Best Valentines Day Gifts for the Men in Your Life. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. Ehsani AH, Nasimi M, Bigdelo Z. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291919/). 9 , 10 These findings suggest that immuneinduced viral reactivation - rather than Characterization of the inflammatory cell infiltrate in herald patches and fully developed eruptions of pityriasis rosea. Get useful, helpful and relevant health + wellness information. Our reported case adds to the other findings regarding the association of PR with SARS-CoV-2 infection, in the context of the pandemic, suggesting the need to test patients with PR skin lesions for SARS-CoV-2 infection. Pityriasis rosea is a common condition that causes discolored patches on your skin. Learning points: Treatment with topical 0.1% triamcinolone acetonide twice daily showed partial response after seven days. An official website of the United States government. A 52-year-old Thai woman with a one-year history of recurrent glioblastoma was admitted to our hospital for a planned targeted therapy. Sriphojanart T, Khunkhet S, Suchonwanit P. A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata. An official website of the United States government. 2022 Jul 21;14(7):e27108. This site needs JavaScript to work properly. How quickly did it come on, and did my boyfriend also have it? The symptoms of pityriasis rosea usually develop in stages: Pityriasis rosea doesnt hurt. Dermatol Ther. A spectrum of cutaneous reactions to SARs-CoV-2 (COVID-19) vaccines have been reported in the literature. 2021 May;62(2):e333-e334. Also, topical medication with dermatocorticosteroids and emollients was associated. Bookshelf However, if you scratch your patches, you may break your skin, leading to an infection that can cause pain. Rashes should be considered a "key diagnostic sign" of Covid-19, according to a study, which found 8% of people who test positive for the virus have some form of rash. Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. It should clear your body in six to eight weeks. Pearls and pitfalls: Adverse cutaneous reactions after COVID-19 vaccination. Luckily, it's not contagious. Had I started new medication? (A) Dermoscopic features: dotted and linear vessels forming a network on a yellowish background with some whitish peripheral scales (original magnification x20). Central dusky-red erythematous on some plaques (A); almost all lesions fading with associated post-inflammatory hyperpigmentation after treatment (B). doi: 10.1111/bjd.20143. Drago F, Ciccarese G, Parodi A. Pityriasis rosea and pityriasis rosea-like eruptions: How to distinguish them? National Library of Medicine *Correspondence: Poonkiat Suchonwanit, poonkiat@hotmail.com, ORCID: Kanchana Leerunyakul orcid.org/0000-0002-0669-5611Kallapan Pakornphadungsit orcid.org/0000-0003-4783-0282Poonkiat Suchonwanit orcid.org/0000-0001-9723-0563, COVID-19 Associated Cutaneous Manifestations and COVID-19 Vaccine Related Skin Reactions, View all ", Though there's no single-known cause, King says, "pityriasis rosea is associated with reactivation of herpesviruses 6 and 7 [HHV-6 and HHV-7, respectively], which cause the primary rash, roseola, in infants. Your healthcare provider can typically diagnose pityriasis rosea after a physical exam. Clipboard, Search History, and several other advanced features are temporarily unavailable. 2022 Aug;35(8):e15601. While it can spread all over the entire body, PR usually favors the trunk, says Christina Lam, an assistant professor of dermatology at Boston University School of Medicine and dermatologist at Boston Medical Center. Akdas E, Ilter N, Ogut B, Erdem O. Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. We evaluated the clinical and pathologic spectrum of mucocutaneous reactions following COVID-19 vaccines, observed consecutively within three large tertiary Centers of the Metropolitan City of Milan . Factors affecting the severity of central centrifugal cicatricial alopecia. doi: 10.1111/dth.15601. "There's some emerging data where there are certain skin rashes that seem to be more associated with the COVID vaccine, and pityriasis rosea is one them. Cebeci Kahraman F, Sava Erdoan S, Akta ND, Albayrak H, Trkmen D, Borlu M, Arca DA, Demirba A, Akbayrak A, Polat Ekinci A, Gkek GE, elik HA, Taolar MK, An , Temiz SA, Hazinedar E, Ayhan E, Hzl P, Solak E, Kl A, Ylmaz E. J Cosmet Dermatol. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. One case of pityriasis rosea is reported in a patient infected with COVID-19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. Unauthorized use of these marks is strictly prohibited. SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. Br J Dermatol 2021. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. Suchonwanit P, Leerunyakul K, Kositkuljorn C. Cutaneous manifestations in COVID-19: Lessons learned from current evidence. The site is secure. Careers. A few days later, the cluster came: Ten little dots arranged themselves in a perfect alien-like crop circle on my upper back, and they itched so much that I scratched them raw. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Ethical review and approval was not required for the study on human participants in accordance with the local legislation and institutional requirements. Following the national COVID-19 vaccination guidelines, she received a shot of ChAdOx1 nCoV-19 (AZD1222) vaccine before the therapy. Clipboard, Search History, and several other advanced features are temporarily unavailable. Moreover, COVID-19 may solely induce human herpesvirus reactivation through the immunomodulatory ability of SARS-CoV-2 to reactivate latent viruses (8, 9). NCI CPTC Antibody Characterization Program. Oueijan RI, Hill OR, Ahiawodzi PD, Fasinu PS, Thompson DK. These strains of the herpes virus arent related to the strains that cause cold sores or genital herpes. J Eur Acad Dermatol Venereol 2020;34:e2123. Epub 2021 May 29. Europe PMC is an archive of life sciences journal literature. and transmitted securely. The etiopathogenesis of PR is still unknown, but is frequently associated with episodes of upper respiratory tract infections. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (b) haematoxylineosin, original magnification 20. Bookshelf Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. Pityriasis rosea. "Any type of stress on the body can sometimes [cause them, and] any vaccine, not just the COVID one.". Clipboard, Search History, and several other advanced features are temporarily unavailable. Vote for your favorite beauty products now! doi: 10.1111/jdv.17498. Unauthorized use of these marks is strictly prohibited. An official website of the United States government. Pityriasis rosea (PR)-like eruption is a cutaneous complication associated with several medications and vaccinations. Int J Infect Dis. While home remedies are safe for most people, its a good idea to check with your healthcare provider before trying some of the following options. Bethesda, MD 20894, Web Policies Department of Dermatology, Graduate School of Medicine, Kyusyu University, Japan. Numerous scattered erythematous plaques with fine scale oriented along skin cleavage lines, most appreciable on the upper portion of the chest. Do the medications have any side effects? Histopathologic features: (B) microscopic image at a low power field showing psoriasiform epidermal hyperplasia, perivascular infiltration, and interface dermatitis (hematoxylin-eosin; scale bar represents 100 m); (C) microscopic image at a high power field showing focal spongiotic dermatitis, interface dermatitis, and perivascular infiltration of lymphocytes and eosinophils (hematoxylin-eosin; scale bar represents 40 m). sharing sensitive information, make sure youre on a federal Pityriasis rosea-like rash after messenger RNA COVID-19 - PubMed and transmitted securely. Accessibility Due to the temporal relationship between vaccination and onset of rash, COVID-19 vaccination was the most likely etiology. Foods that have anti-inflammatory properties include: Foods that may increase inflammation include: There isnt any way to prevent pityriasis rosea. Pityriasis Lichenoides - Dermatologic Disorders - Merck Manuals Moreover, while dermoscopy may facilitate the diagnosis of PR, its utility for atypical PR or PR-like lesions is still limited. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. Women and young people are most likely to have these reactions. However, several adverse effects of COVID-19 vaccination have been identified. Adverse cutaneous reactions following COVID-19 vaccines have increased, highlighting not only how SARS-CoV-2 infection but also COVID-19 vaccines may induce adverse cutaneous manifestations. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Unable to load your collection due to an error, Unable to load your delegates due to an error. The site is secure. Additional evidence that pityriasis rosea is associated with reactivation of human herpesvirus-6 and -7. Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. Studies show that some skin conditions may appear with COVID-19, including pityriasis rosea. PS conceptualized the case report and revised the manuscript. In approximately 50% of people with pityriasis rosea, the patches itch. The .gov means its official. "It's usually not from head to toe that's more atypical but there are some people that get it more in the groin area or in the armpit rather than on the trunk predominantly, which is just a variant.". This tiny glimpse of her natural texture is thrilling. The https:// ensures that you are connecting to the Among patients who received inactivated vaccines, another case of PR-like eruption was reported four days after the first dose of CoronaVac (SinoVac) (1). 8 Types of Rashes That Can Be a Sign of COVID-19 - Health 2022 May;11(2):222-225. doi: 10.7774/cevr.2022.11.2.222. PMC The .gov means its official. Please enable it to take advantage of the complete set of features! Pityriasis Rosea Rash: Symptoms, Causes, & Treatment - WebMD FOIA 2022 Mar 9;35(3):342-343. doi: 10.1080/08998280.2022.2044742. This patch is the herald or mother patch. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection J Eur Acad Dermatol Venereol 2016; 30: 544545. Its important to pay attention to your skin. Accessibility Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. Many Americans become infected with them at an early age. Pityriasis rosea (pih-tuh-RY-uh-sis ROH-zee-uh) is a common skin condition that causes patches of your skin to develop raised, scaly rashes. COVID-19; Vaccination; pityriasis rosea. Before In: Jameson J, Fauci AS, Kasper DL, et al., eds. F. Drago, G. Ciccarese, A. Parodi Lasers Med Sci. doi: 10.1111/jdv.12942, 13. What at-home treatments do you recommend? 18. The Covid Symptom Study. She diagnosed it as pityriasis rosea, a benign but frustratingly itchy rash that in her words just happens sometimes. Medicines (Basel). Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. -, Broccolo F., Drago F., Careddu A.M., et al. [Epub ahead of print]. Conflicts of Interests: The authors declare there are no competing interests. Pityriasis Rosea as a Possible Complication of Vaccination Against COVID-19 Disclaimer. J Eur Acad Dermatol Venereol. Parakeratosis with minimal acanthosis and spongiosis of the epidermis. If you have pityriasis rosea, it can generally be well-managed without any treatment. Martn Enguix D, Salazar Nievas MDC, Martn Romero DT. Figure 2. Rare Heterogeneous Adverse Events Associated with mRNA-Based COVID-19 Vaccines: A Systematic Review. (2019) 34:185764. Medicine (Baltimore). Federal government websites often end in .gov or .mil. Could covid-19 infection cause pityriasis rosea why? Published by Wolters Kluwer Health, Inc. 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. N Engl J Med 2020; 383: 2603-2615. Policy. Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, et al. Epub 2022 Jan 31. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Cleveland Clinic is a non-profit academic medical center. 2022 Jul 8;101(27):e29823. Anyone can get pityriasis rosea. A more recent letter in the International Journal of Dermatology reported a "unique case of pityriasis rosea following administration of mRNA COVID-19 vaccine." 2023 Feb 9;11(2):397. doi: 10.3390/vaccines11020397. doi: 10.1111/jdv.17316. Theyre both papulosquoamous (pap-you-lo-skway-miss) disorders, which is a term used to characterize skin disorders according to the presence of raised, discolored, scaly patches of skin. Here, we report the first case of PR-like eruption following ChAdOx1 nCoV-19 (Oxford/AstraZeneca) vaccination. From grooming sets to self-care gadgets, we've got them covered. Dermatology. Bookshelf Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. 8600 Rockville Pike HHS Vulnerability Disclosure, Help I figured a very determined mosquito had snuck into my room and attacked me through my tank top. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. -, Carballido Vzquez AM, Morgado B. Pityriasis rosea-like eruption after PfizerBioNTech COVID-19 vaccination. 2022 Aug;20(8):1123-1124. doi: 10.1111/ddg.14784. FOIA Although the exact pathogenesis of PR remains unknown, the endogenous systemic reactivation of HHV (i.e., type 6 and 7) in the skin has been implicated as a precipitating factor. 2020 Sep 25;155(6):273. doi: 10.1016/j.medcli.2020.05.024. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Federal government websites often end in .gov or .mil. Apply a moisturizer, calamine lotion or a nonprescription . Lastly, Hartman says PR can present differently in patients with darker skin: "The characteristic erythematous plaques may appear more hyperpigmented or violaceous in darker skin types. Published by Elsevier Inc. Pityriasis rosea. The significance of investigating clinical, histopathologic and virological features in pityriasis rosea and pityriasis rosea-like eruptions following COVID-19 vaccinations. These patches are smaller than the herald patch they range from 1 to 2 cm and are often called daughter patches. The https:// ensures that you are connecting to the 2021 Sep;35(9):e546-e548. Bethesda, MD 20894, Web Policies The https:// ensures that you are connecting to the COVID-19 vaccines reactions, type I hypersensitivity reactions (such as urticaria, angioedema, and anaphylaxis), . 2021;185(2):e34. doi: 10.1016/j.jdcr.2018.04.002, 12. However, if you experience any symptoms, therapy can provide relief. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). Pityriasis rosea usually resolves on its own without treatment in most cases, King says, but topical corticosteroids can be used for itchy control if necessary, which is what I used. Once its gone, you likely wont develop it again. Epub 2022 May 3. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. HHS Vulnerability Disclosure, Help -, Drago F, Ciccarese G, Javor S, Parodi A. Vaccineinduced pityriasis rosea and pityriasis rosealike eruptions: a review of the literature. Pityriasis rosea, COVID19 and vaccination: new keys to understand an